Clinical data showing efficacy and safety profile
In early in vitro studies and in an in vivo clinical study DermaSys® showed significant superiority in terms of skin penetration of ibuprofen. TIB200, a topical gel combining the well-known analgesic ibuprofen with the DermaSys® delivery system, has been shown to achieve superior penetration through human skin compared with other commercially available topical ibuprofen gels.
In a proof of concept study in a model of UV-induced erythema and pain, the efficacy and safety of TIB200 was assessed against a market-leading ibuprofen gel, oral ibuprofen, as well as a placebo gel. TIB200 outperformed both topical and oral comparators, and placebo.